Percutaneous coronary intervention versus coronary artery bypass grafting for stenotic lesions after Kawasaki disease

  • Muta H
  • Ishii M
  • 6

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Abstract

OBJECTIVE: To compare the long-term efficacy of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) for stenotic lesions after Kawasaki disease. STUDY DESIGN: Questionnaires were sent to pediatricians in Japan in hospitals with 100 or more beds. A total of 1637 questionnaires were sent, and 1347 (82%) were returned. The primary endpoints of the study were the composite of deaths from any cause and the Q-wave myocardial infarction. The secondary endpoints were the repeat-revascularization for the target vessel. RESULTS: A total of 67 patients underwent PCI and 81 patients underwent CABG. Although the rates of the primary endpoints did not differ between the groups (hazard ratio 1.35 [95% confidence interval 0.29 to 6.32], P=.7), the rate of the secondary endpoints in the PCI group was significantly higher than that in the CABG group (hazard ratio 2.23 [95% confidence interval 1.04 to 4.76], P=.04). The benefit with CABG for the secondary endpoints was notable in patients younger than 12 years old, and who had ischemic change. CONCLUSIONS: PCI after Kawasaki disease resulted in a lower efficacy in comparison to CABG because of increased repeat-revascularization procedures.

Author-supplied keywords

  • Age Factors
  • Angioplasty, Balloon, Coronary/methods/ statistics
  • Child, Preschool
  • Coronary Angiography
  • Coronary Artery Bypass/methods/ statistics & numer
  • Coronary Restenosis/epidemiology/radiography
  • Coronary Stenosis/etiology/radiography/surgery/ th
  • Coronary Vessels/pathology/surgery
  • Electrocardiography
  • Female
  • Hospitals
  • Humans
  • Japan
  • Male
  • Mucocutaneous Lymph Node Syndrome/ complications
  • Myocardial Infarction/epidemiology/radiography
  • Questionnaires
  • Time Factors
  • Treatment Outcome

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Authors

  • H Muta

  • M Ishii

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