Perioperative magnesium infusion and postoperative pain

  • Wilder-Smith C
  • Knöpfli R
  • Wilder-Smith O
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Abstract

NMDA receptor activation is considered one of the mechanisms involved in postoperative pain and hypersensitivity. Magnesium is the physiological blocker of the NMDA-receptor-complex-associated calcium ionophore. The aim of this study was to determine if a pre-, intra- and postoperative infusion of magnesium would reduce postoperative pain.

Author-supplied keywords

  • Analgesia
  • Hyperalgesia
  • Hysterectomy
  • Magnesium
  • Pain sensitisation
  • Postoperative pain

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Authors

  • C. H. Wilder-Smith

  • R. Knöpfli

  • O. H.G. Wilder-Smith

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