Phenotypic variation of retinal pigment epithelium in age-related macular degeneration.

  • Guidry C
  • Medeiros N
  • Curcio C
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Abstract

To determine whether retinal pigment epithelium (RPE) in eyes with age-related macular degeneration (ARMD) express vimentin and alpha smooth muscle actin (alphaSMA), two cytoskeletal proteins associated with phenotypic variation in culture.

Author-supplied keywords

  • 80 and over
  • Actins
  • Actins: metabolism
  • Aged
  • Female
  • Fluorescent Antibody Technique
  • Glial Fibrillary Acidic Protein
  • Glial Fibrillary Acidic Protein: metabolism
  • Humans
  • Indirect
  • Macular Degeneration
  • Macular Degeneration: metabolism
  • Macular Degeneration: pathology
  • Male
  • Phenotype
  • Pigment Epithelium of Eye
  • Pigment Epithelium of Eye: metabolism
  • Pigment Epithelium of Eye: pathology
  • Vimentin
  • Vimentin: metabolism

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Authors

  • Clyde Guidry

  • Nancy E Medeiros

  • Christine a Curcio

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