The formation of surface-grafted polypeptide films and interfaces via N-carboxyanhydride ring-opening polymerization (NCA-ROP) holds great potential for the facile preparation of next-generation multifunctional and responsive materials with excellent biocompatibility, biodegradability, tunable conformations and chemical functionalities. Therefore, the aim of this feature article is to provide a topical review of developments in the area of polypeptide films derived through NCA-ROP. It is evident that studies reported thus far have only started to unveil the full potential of peptide-based interfaces and materials, and with continued advancements it is anticipated that the strategic combination of NCA-ROP with modern synthetic chemistries will continue to yield versatile platforms for broader applications in the fields of polymer therapeutics, tissue engineering, (bio)nanocoatings, (bio)chemosensors, catalysis and separation technologies. © 2014 Partner Organisations.
CITATION STYLE
Wibowo, S. H., Sulistio, A., Wong, E. H. H., Blencowe, A., & Qiao, G. G. (2014). Polypeptide films via N-carboxyanhydride ring-opening polymerization (NCA-ROP): Past, present and future. Chemical Communications, 50(39), 4971–4988. https://doi.org/10.1039/c4cc00293h
Mendeley helps you to discover research relevant for your work.