Positioning to get out of meiosis: The asymmetry of division

  • Brunet S
  • Verlhac M
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Abstract

During meiosis, mammalian oocytes undergo two successive cell divisions without an intermediate replicative phase. This brief period, called 'meiotic maturation', is crucial for the formation of an egg capable of being fertilized and of generating viable and euploid offspring.

Author-supplied keywords

  • Asymmetric divisions
  • Cytoskeleton
  • Oocyte
  • Pre- and post-ovulatory ageing

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