Postcode prescribing in psychiatry. {Clozapine} in an {English} county.

  • Purcell H
  • Lewis S
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Examined variations in clozapine prescribing, used in treating schizophrenia symptoms, in all 12 NHS trusts with catchment area mental health services in one English county, over a 2-yr period. The authors attempted to explain any inequalities in prescribing either arising as variations in need or in provision, since analysis of such variations can reveal insights into policy and practice. A 34–fold variation between trusts in rates of clozapine provision was found after adjusting for measures of local population need. This variation did not change over the 2 yrs examined. It was not explained by differences in resource level. The evidence base is strong for the effectiveness and likely cost–effectiveness of clozapine in severe schizophrenia. The data indicated that variations in evidence–based clinical practice at the provider level led to the wide variation in clozapine prescribing. (PsycINFO Database Record (c) 2014 APA, all rights reserved)

Author-supplied keywords

  • 2 yr study
  • Clozapine
  • Drug Administration Methods
  • Drug Therapy
  • Prescribing (Drugs)
  • Schizophrenia
  • variation in prescribing of clozapine for symptom

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  • Helen Purcell

  • Shon Lewis

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