Journal article

Potential anticancer activity of turmeric (Curcuma longa)

Kuttan R, Bhanumathy P, Nirmala K, George M ...see all

Cancer Letters, vol. 29, issue 2 (1985) pp. 197-202

  • 33

    Readers

    Mendeley users who have this article in their library.
  • 413

    Citations

    Citations of this article.
Sign in to save reference

Abstract

Anticancer activity of the rhizomes of turmeric was evaluated in vitro using tissue culture methods and in vivo in mice using Dalton's lymphoma cells grown as ascites form. Turmeric extract inhibited the cell growth in Chinese Hamster Ovary (CHO) cells at a concentration of 0.4 mg/ml and was cytotoxic to lymphocytes and Dalton's lymphoma cells at the same concentration. Cytotoxic effect was found within 30 min at room temperature (30??C). The active constituent was found to be 'curcumin' which showed cytotoxicity to lymphocytes and Dalton's lymphoma cells at a concentration of 4 ??g/ml. Initial experiments indicated that turmeric extract and curcumin reduced the development of animal tumours. ?? 1985.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text

Authors

  • Ramadasan Kuttan

  • P. Bhanumathy

  • K. Nirmala

  • M. C. George

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free