Potentially inappropriate medication use in a city of Southeast Brazil

  • Pinto M
  • Ferré F
  • Pinheiro M
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Abstract

Potentially inappropriate medication use by the Diamantina (Minas Gerais State) population was investigated by analyzing medicine consumption, self-medication, polypharmacy and drug interactions of medicines prescribed among those interviewed. Level of knowledge about rational drug use and its relationship to socio-economic variables was also evaluated using a semi-structured questionnaire. This survey was based on stratified sampling of 423 individuals selected randomly. The prevalence of prescription drug consumption was 42.32% (n=179) and cardiovascular drugs were the most prescribed. Drug interactions were found in 45.81% (n=82) of prescriptions and 92.68% (n=76) of these interactions were moderate, with co-administration of cardiovascular drugs occurring in more than half of the cases. The inappropriate use of medication, according to Beers criteria, occurred in 44.73% of prescriptions to the elderly. The prevalence of self-medication was 63.34% (n=268) while 21.99% (n=91) of individuals administered medications to their children without formal prescriptions, where this practice was associated to analgesic/antipyretic consumption. The population showed a high prevalence of inappropriate use of drugs across all strata of society, representing an issue requiring effective actions to promote rational use of medicines.

Author-supplied keywords

  • Automedicação/estatística & dados numérico
  • Farmacoepidemiologia/classificação
  • Seres Humanos
  • Uso Excessivo de Medicamentos Prescritos/estatísti
  • Uso Indevido de Medicamentos sob Prescrição

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Authors

  • Mauro Cunha Xavier Pinto

  • Felipe Ferré

  • Marcos Luciano Pimenta Pinheiro

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