Pregnancies resulting from in vitro matured oocytes retrieved from patients with polycystic ovary syndrome after priming with human chorionic gonadotropin

  • Chian R
  • Buckett W
  • Too L
 et al. 
  • 15

    Readers

    Mendeley users who have this article in their library.
  • 71

    Citations

    Citations of this article.

Abstract

Objective: To describe pregnancies that resulted from in vitro matured oocytes derived from two unstimulated, anovulatory patients with polycystic ovary syndrome after priming with hCG before oocyte retrieval. Design: Case series. Setting: McGill Reproductive Center, Royal Victoria Hospital, McGill University. Patient(s): Two women with polycystic ovary syndrome. Intervention(s): Progesterone induction of a withdrawal bleeding episode. The administration of subcutaneous hCG 36 hours before oocyte retrieval in a natural menstrual cycle. In vitro maturation of immature oocytes, fertilization, and ET. Luteal support with oral estrogen and progesterone. Main Outcome Measure(s): Pregnancy outcome. Result(s): Two clinical pregnancies were confirmed after oocyte maturation in vitro, fertilization with intracytoplasmic sperm injection, and ET. Conclusion(s): The administration of hCG 36 hours before harvesting of immature oocytes may improve the maturational and developmental competence of the oocytes and the pregnancy rates of unstimulated patients with polycystic ovary syndrome.

Author-supplied keywords

  • Immature oocytes
  • Maturation
  • PCOS
  • Pregnancy
  • hCG

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Ri Cheng Chian

  • William M. Buckett

  • Loy Lan Too

  • Seang Lin Tan

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free