Prevalence and Antibiogram of Methicilin-Susceptible Staphylococcus aureus (MSSA) Isolated from Raw Milk of Asymptomatic Cows In Abeokuta, Nigeria

Abstract

Most S. aureus show resistance to methicillin and are non-beta-lactam sensitive (MSSA) but are also resistant to other antibiotics and have been associated with mastitis, nosocomial infections, food poisoning, septicemia and other diseases in animals and man. No study has identified S. aureus in milk of apparently healthy cows in Abeokuta and its environment. In this study, 7 of 9 isolates S. aureus (77.8%) were MSSA and they all showed good susceptibility to all the routinely used antibiotics in Abeokuta viz: Augmentin, Cefuroxime, Gentamycin, Cotrimoxazole, Ofloxacin Tetracycline and Perfloxcin. The S. aureus isolates also show a low MIC values of 2-4 ug/ml to all the antibiotics used, except cotrimoxazole where a value of 8 ug/ml was recorded indicating an emergence of resistance to the cotrimazole antimicrobial agents Rapidly emerging multi-drug resistant strains of MSSA pose a threat to public health and make treatment failure quite imminent, therefore African countries, including Nigeria should consider having efficient control over misuse of antibiotics.