Prevalence of cardiomyopathy in italian asymptomatic children with electrocardiographic T-wave inversion at preparticipation screening

  • Migliore F
  • Zorzi A
  • Michieli P
 et al. 
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BACKGROUND: T-wave inversion on a 12-lead ECG is usually dismissed in young people as normal persistence of the juvenile pattern of repolarization. However, T-wave inversion is a common ECG abnormality of cardiomyopathies such as hypertrophic cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy, which are leading causes of sudden cardiac death in athletes. We prospectively assessed the prevalence, age relation, and underlying cardiomyopathy of T-wave inversion in children undergoing preparticipation screening., METHODS AND RESULTS: The study population included 2765 consecutive Italian children (1914 male participants; mean age, 13.9+/-2.2 years; range 8-18 years) undergoing preparticipation screening including an ECG. Of 229 children (8%) who underwent further evaluation because of positive findings at initial preparticipation screening, 33 (1.2%) were diagnosed with cardiovascular disease. T-wave inversion was recorded in 158 children (5.7%) and was localized in the right precordial leads in 131 (4.7%). The prevalence of right precordial T-wave inversion decreased significantly with increasing age (8.4% in children 14 years; P

Author-supplied keywords

  • arrhythmogenic right ventricular dysplasia
  • athletes
  • cardiomyopathy
  • child
  • electrocardiography
  • hypertrophic

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  • Federico Migliore

  • Alessandro Zorzi

  • Pierantonio Michieli

  • Martina Perazzolo Marra

  • Mariachiara Siciliano

  • Ilaria Rigato

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