Productie en klinische toepassingen van [15O]-gelabelde gassen

  • Van Rij C
  • Sturkenboom M
  • Luurtsema G
 et al. 
  • 17


    Mendeley users who have this article in their library.
  • 0


    Citations of this article.


Production and clinical application of [15O]-labelled gasses Positron Emission Tomography (PET) is used for in vivo measurement of physiological processes, both qualitatively and quantitatively. 15O is a radionuclide that is regularly used in PET. Next to its use in [15O]H2 O, it is also used as a radioactive gas. [ 15O]O2 , [15O]CO and [15O]CO2 are inhaled for use in both cardiology and neurology for determining oxygen metabolism, blood volume and cerebral perfusion. [15O]-gasses have a very short half-life of about 2 minutes, which makes validation of the production process, rapid synthesis and rapid analysis inevitable. This requires extensive logistics and the use of an on-site cyclotron.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

  • SCOPUS: 2-s2.0-41649120524
  • ISSN: 00316911
  • SGR: 41649120524
  • PUI: 351480493

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free