ProfDist: A tool for the construction of large phylogenetic trees based on profile distances

  • Friedrich J
  • Dandekar T
  • Wolf M
 et al. 
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SUMMARY: ProfDist is a user-friendly software package using the profile-neighbor-joining method (PNJ) in inferring phylogenies based on profile distances on DNA or RNA sequences. It is a tool for reconstructing and visualizing large phylogenetic trees providing new and standard features with a special focus on time efficency, robustness and accuracy. AVAILABILITY: A Windows version of ProfDist comes with a graphical user interface and is freely available at

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  • Joachim Friedrich

  • Thomas Dandekar

  • Matthias Wolf

  • Tobias Müller

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