Prolonged use of benzodiazepines is associated with childhood trauma in opioid-maintained patients

  • Vogel M
  • Dursteler-Macfarland K
  • Walter M
 et al. 
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Abstract

BACKGROUND: Benzodiazepine (BZD) misuse in opioid-maintained patients is widespread and has been related to poorer treatment success. Associated factors, in particular, traumatic childhood experiences, have not been investigated extensively. METHODS: Cross-sectional survey including the childhood trauma questionnaire (CTQ) and clinical data among 193 patients prescribed oral opioids or injectable diacetylmorphine for opioid dependence. RESULTS: BZD use was prevalent (61%) and the burden of childhood traumatic experiences was high with 67% reporting at least one trauma subscore of moderate-to-severe level. In univariate analysis, CTQ-subcategories "emotional abuse" (p

Author-supplied keywords

  • Age Factors
  • Analgesics, Opioid/adverse effects/therapeutic use
  • Benzodiazepines/adverse effects/*therapeutic use/u
  • Child
  • Child Abuse/*psychology/statistics & numerical dat
  • Comorbidity
  • Cross-Sectional Studies
  • Female
  • Humans
  • Logistic Models
  • Male
  • Methadone/therapeutic use/urine
  • Opiate Substitution Treatment/methods/*psychology/
  • Opioid-Related Disorders/drug therapy/*epidemiolog
  • Psychiatric Status Rating Scales
  • Questionnaires
  • Substance-Related Disorders/drug therapy/*epidemio
  • Time Factors
  • Violence

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Authors

  • M Vogel

  • K M Dursteler-Macfarland

  • M Walter

  • J Strasser

  • S Fehr

  • L Prieto

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