Promoter architecture and the evolvability of gene expression

  • Tirosh I
  • Barkai N
  • Verstrepen K
 et al. 
  • 3


    Mendeley users who have this article in their library.
  • N/A


    Citations of this article.


Evolutionary changes in gene expression are a main driver of phenotypic evolution. In yeast, genes that have rapidly diverged in expression are associated with particular promoter features, including the presence of a TATA box, a nucleosome-covered promoter and unstable tracts of tandem repeats. Here, we discuss how these promoter properties may confer an inherent capacity for flexibility of expression.

Author-supplied keywords

  • Biomedicine general
  • Life Sciences
  • general

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Itay Tirosh

  • Naama Barkai

  • Kevin J Verstrepen

  • MC King

  • AC Wilson

  • EH Davidson

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free