Protein translocon at the Arabidopsis outer chloroplast membrane

  • Hiltbrunner A
  • Bauer J
  • Alvarez-Huerta M
 et al. 
  • 10

    Readers

    Mendeley users who have this article in their library.
  • 52

    Citations

    Citations of this article.

Abstract

Chloroplasts are organelles essential for the photoautotrophic growth of plants. Their biogenesis from undif- ferentiated proplastids is triggered by light and requires the import of hundreds of different precursor proteins from the cytoplasm. Cleavable N-terminal transit sequences target the precursors to the chloroplast where translocon complexes at the outer (Toc complex) and inner (Tic complex) envelope membranes enable their import. In pea, the Toc complex is trimeric consisting of two surface-exposed GTP-binding proteins (Toc159 and Toc34) involved in precursor recogni- tion and Toc75 forming an aequeous protein-conducting channel. Completion of the Arabidopsis genome has revealed an unexpected complexity of predicted components of the Toc complex in this plant model organism: four genes en- code homologs of Toc159, two encode homologs of Toc34, but only one encodes a likely functional homolog of Toc75. The availability of the genomic sequence data and powerful molecular genetic techniques in Arabidopsis set the stage to unravel the mechanisms of chloroplast protein import in unprecedented depth.

Author-supplied keywords

  • arabidopsis
  • chloroplast
  • genetics
  • hiltbrunner
  • les chloroplastes sont des
  • organites essentiels pour la
  • protein import
  • résumé

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text

Authors

  • A. Hiltbrunner

  • J. Bauer

  • M. Alvarez-Huerta

  • F. Kessler

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free