Proteins as micro viscosimeters: Brownian motion revisited

  • Lavalette D
  • Hink M
  • Tourbez M
 et al. 
  • 20

    Readers

    Mendeley users who have this article in their library.
  • 31

    Citations

    Citations of this article.

Abstract

Translational and rotational diffusion coefficients of proteins in solution strongly deviate from the Stokes-Einstein laws when the ambient viscosity is induced by macromolecular co-solutes rather than by a solvent of negligible size as was assumed by A. Einstein one century ago for deriving the laws of Brownian motion and diffusion. Rotational and translational motions experience different micro viscosities and both become a function of the size ratio of protein and macromolecular co-solute. Possible consequences upon fluorescence spectroscopy observations of diffusing proteins within living cells are discussed.

Author-supplied keywords

  • Brownian motion
  • Diffusion in the cell
  • Microscopic hydrodynamics
  • Microviscosity

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text

Authors

  • Daniel Lavalette

  • Mark A. Hink

  • Martine Tourbez

  • Catherine Tétreau

  • Antonie J. Visser

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free