Psychiatric disorders and psychotropic medication use in elderly persons with diabetes

  • D. F
  • J. W
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Type 2 diabetes is rising in epidemic proportions due to increases in lifestyle risk factors and the aging of the population. Cognitive disorders, depression, and alcohol abuse are notable psychiatric conditions that clinicians treat in patients with diabetes. Cognitive deficits and dementia prevalence are higher in persons with diabetes. While prevalence of depression is high, it is recognized and treated in fewer than 25% of persons with diabetes. Heavy alcohol intake increases the risk of developing diabetes and worsens existing diabetes. Psychotropic medications are prescribed for many conditions in diabetes. Clinicians treat painful diabetic peripheral neuropathy with antidepressants and mood stabilizers, which may deliver low efficacy or have notable risks in this population. Antidepressants and atypical antipsychotics are prescribed for depression and dementia, respectively, and may have side effects that can worsen diabetes. Thus, in older persons with type 2 diabetes, treatment with psychotropic medications requires careful consideration of risks and benefits.

Author-supplied keywords

  • *mental disease/dm [Disease Management]
  • *mental disease/dt [Drug Therapy]
  • *mental disease/ep [Epidemiology]
  • *mental disease/pc [Prevention]
  • *non insulin dependent diabetes mellitus/dm [Disea
  • *non insulin dependent diabetes mellitus/ep [Epide
  • *non insulin dependent diabetes mellitus/et [Etiol
  • *psychotropic agent/ae [Adverse Drug Reaction]
  • *psychotropic agent/cm [Drug Comparison]
  • *psychotropic agent/ct [Clinical Trial]
  • *psychotropic agent/do [Drug Dose]
  • *psychotropic agent/dt [Drug Therapy]
  • *psychotropic agent/pd [Pharmacology]
  • *psychotropic agent/pk [Pharmacokinetics]
  • Alzheimer disease/dt [Drug Therapy]
  • Alzheimer disease/pc [Prevention]
  • QT prolongation/si [Side Effect]
  • agitation
  • alcohol abuse
  • amfebutamone/ae [Adverse Drug Reaction]
  • amfebutamone/ct [Clinical Trial]
  • amfebutamone/dt [Drug Therapy]
  • anticholinergic effect
  • anticonvulsive agent/ae [Adverse Drug Reaction]
  • anticonvulsive agent/dt [Drug Therapy]
  • antidepressant agent/ae [Adverse Drug Reaction]
  • antidepressant agent/cm [Drug Comparison]
  • antidepressant agent/ct [Clinical Trial]
  • antidepressant agent/do [Drug Dose]
  • antidepressant agent/dt [Drug Therapy]
  • antidepressant agent/pd [Pharmacology]
  • aripiprazole/ae [Adverse Drug Reaction]
  • atypical antipsychotic agent/ae [Adverse Drug Reac
  • atypical antipsychotic agent/cm [Drug Comparison]
  • atypical antipsychotic agent/dt [Drug Therapy]
  • behavior therapy
  • caregiver support
  • cholinesterase inhibitor/do [Drug Dose]
  • cholinesterase inhibitor/dt [Drug Therapy]
  • cholinesterase inhibitor/pd [Pharmacology]
  • citalopram/ae [Adverse Drug Reaction]
  • citalopram/ct [Clinical Trial]
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  • citalopram/dt [Drug Therapy]
  • clinical examination
  • clinical trial
  • clozapine/ae [Adverse Drug Reaction]
  • cognitive defect/dt [Drug Therapy]
  • cognitive defect/ep [Epidemiology]
  • cognitive defect/pc [Prevention]
  • confusion/si [Side Effect]
  • dementia/dt [Drug Therapy]
  • dementia/ep [Epidemiology]
  • dementia/pc [Prevention]
  • depression/dm [Disease Management]
  • depression/dt [Drug Therapy]
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  • depression/et [Etiology]
  • depression/th [Therapy]
  • diet restriction
  • disease association
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  • drug efficacy
  • drug mechanism
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  • duloxetine/ct [Clinical Trial]
  • duloxetine/dt [Drug Therapy]
  • duloxetine/pd [Pharmacology]
  • elderly care
  • endocrine disease/si [Side Effect]
  • escitalopram/ae [Adverse Drug Reaction]
  • escitalopram/ct [Clinical Trial]
  • escitalopram/dt [Drug Therapy]
  • exercise
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  • fluoxetine/cm [Drug Comparison]
  • fluoxetine/ct [Clinical Trial]
  • fluoxetine/dt [Drug Therapy]
  • galantamine/dt [Drug Therapy]
  • galantamine/pd [Pharmacology]
  • glucose blood level
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  • health care management
  • human
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  • insulin resistance/si [Side Effect]
  • insulin/dt [Drug Therapy]
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  • memantine/dt [Drug Therapy]
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  • mirtazapine/ae [Adverse Drug Reaction]
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  • n methyl dextro aspartic acid receptor blocking ag
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  • neuroleptic agent/ae [Adverse Drug Reaction]
  • neuroleptic agent/cm [Drug Comparison]
  • neuroleptic agent/dt [Drug Therapy]
  • olanzapine/ae [Adverse Drug Reaction]
  • olanzapine/dt [Drug Therapy]
  • orthostatic hypotension/si [Side Effect]
  • outcome assessment
  • peripheral neuropathy/dt [Drug Therapy]
  • prevalence
  • psychosis/dt [Drug Therapy]
  • psychotherapy
  • quetiapine/ae [Adverse Drug Reaction]
  • quetiapine/dt [Drug Therapy]
  • review
  • risk factor
  • risperidone/ae [Adverse Drug Reaction]
  • risperidone/dt [Drug Therapy]
  • rivastigmine/dt [Drug Therapy]
  • sedation
  • self care
  • serotonin uptake inhibitor/ae [Adverse Drug Reacti
  • serotonin uptake inhibitor/cm [Drug Comparison]
  • serotonin uptake inhibitor/ct [Clinical Trial]
  • serotonin uptake inhibitor/do [Drug Dose]
  • serotonin uptake inhibitor/dt [Drug Therapy]
  • serotonin uptake inhibitor/pd [Pharmacology]
  • sertraline/ae [Adverse Drug Reaction]
  • sertraline/cm [Drug Comparison]
  • sertraline/ct [Clinical Trial]
  • sertraline/do [Drug Dose]
  • sertraline/dt [Drug Therapy]
  • side effect/si [Side Effect]
  • somnolence/si [Side Effect]
  • systematic review
  • tricyclic antidepressant agent/ae [Adverse Drug Re
  • tricyclic antidepressant agent/ct [Clinical Trial]
  • tricyclic antidepressant agent/do [Drug Dose]
  • tricyclic antidepressant agent/dt [Drug Therapy]
  • tricyclic antidepressant agent/pd [Pharmacology]
  • unindexed drug
  • unspecified side effect/si [Side Effect]
  • venlafaxine/ae [Adverse Drug Reaction]
  • venlafaxine/ct [Clinical Trial]
  • venlafaxine/do [Drug Dose]
  • venlafaxine/dt [Drug Therapy]
  • venlafaxine/pd [Pharmacology]
  • weight gain
  • ziprasidone/ae [Adverse Drug Reaction]

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  • Feil D.

  • Weinreb J.

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