Psychosocial Stress and Cardiovascular Disease Risk: The Role of Physical Activity

  • Hamer M
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Chronic stress and depression are associated with increased risk of cardiovascular disease and poorer prognosis, and physical (in)activity may be a key underlying biobehavioral mechanism. Physical activity has antidepressant effects, and physically fitter, more active individuals seem to be more biologically resilient to psychosocial stressors. This article will present data from a series of population cohort studies and laboratory-based psychophysiological studies to explore the role of physical activity as a protective factor against the effects of psychosocial stress on cardiovascular disease. These mechanisms may improve the treatment and prevention of stress-related illnesses and, thus, has important implications for public health and clinical care of high-risk patients.

Author-supplied keywords

  • bdnf
  • brain-derived
  • c-reactive protein
  • cardiovascular disease
  • crp
  • cvd
  • depression
  • epidemiology
  • hpa
  • hypothalamic-pituitary-adrenal
  • il
  • interleukin
  • necrosis factor
  • neurotrophic factor
  • physical activity
  • psychophysiology
  • stress
  • tnf-
  • tumor

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  • M. Hamer

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