During automated solid-phase peptide synthesis, failure sequences were capped with acetic anhydride. After synthesis, a polymerizable methacrylamide tag was attached to the full-length sequences. Peptide purification was then achieved by polymerizing the full-length sequences, washing away impurities, and cleaving the peptide product from the polymer. © 2014 American Chemical Society.
CITATION STYLE
Zhang, M., Pokharel, D., & Fang, S. (2014). Purification of synthetic peptides using a catching full-length sequence by polymerization approach. Organic Letters, 16(5), 1290–1293. https://doi.org/10.1021/ol403426u
Mendeley helps you to discover research relevant for your work.