Pyocin R1 inhibits active transport in Pseudomonas aeruginosa and depolarizes membrane potential

  • Uratani Y
  • Hoshino T
  • 24


    Mendeley users who have this article in their library.
  • 48


    Citations of this article.


Pyocin R1, a bacteriocin of Pseudomonas aeruginosa, inhibited active transport of proline in the presence of high concentrations of malate and magnesium salt. Pyocin R1 did not affect the respiration of sensitive cells nor induce cell lysis, but it caused a decrease in the intracellular ATP level. In addition, a passive inflow of [14C]thiocyanate anion, a probe of membrane potential, was induced by pyocin R1, showing a depolarization of the cytoplasmic membrane. It is considered that membrane depolarization is a primary action of pyocin R1.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

  • ISBN: 00219193
  • ISSN: 00219193
  • SCOPUS: 2-s2.0-0021345597
  • PUI: 14190954
  • PMID: 6420392
  • SGR: 0021345597


  • Y. Uratani

  • T. Hoshino

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free