Quantum dot-containing polymer particles with thermosensitive fluorescence

  • Generalova A
  • Oleinikov V
  • Sukhanova A
 et al. 
  • 30


    Mendeley users who have this article in their library.
  • 21


    Citations of this article.


Composite polymer particles consisting of a solid poly(acrolein-co-styrene) core and a poly(N-vinylcaprolactam) (PVCL) polymer shell doped with CdSe/ZnS semiconductor quantum dots (QDs) were fabricated. The temperature response of the composite particles was observed as a decrease in their hydrodynamic diameter upon heating above the lower critical solution temperature of the thermosensitive PVCL polymer. Embedding QDs in the PVCL shell yields particles whose fluorescence is sensitive to temperature changes. This sensitivity was determined by the dependence of the QD fluorescence intensity on the distances between them in the PVCL shell, which reversibly change as a result of the temperature-driven conformational changes in the polymer. The QD-containing thermosensitive particles were assembled with protein molecules in such a way that they retained their thermosensitive properties, including the completely reversible temperature dependence of their fluorescence response. The composite particles developed can be used as local temperature sensors, as carriers for biomolecules, as well as in biosensing and various bioassays employing optical detection schemes. © 2012 Elsevier B.V..

Author-supplied keywords

  • Biosensing
  • Colloidal nanocrystals
  • Local temperature
  • Optical encoding
  • Quantum dots
  • Thermosensitive polymer

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Alla GeneralovaInstitut bioorganicheskoj khimii imeni akademikov M M Shemyakina I Yu A Ovchinnikova RAN

  • Vladimir A. Oleinikov

  • Alyona Sukhanova

  • Mikhail V. Artemyev

  • Vitaly P. Zubov

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free