A randomized clinical trial of prophylaxis in children with hemophilia A (the ESPRIT study)

  • Gringeri A
  • Lundin B
  • Von Mackensen S
 et al. 
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Prevention of arthropathy is a major goal of hemophilia treatment. While studies in adults have demonstrated an impact of prophylaxis on the incidence of joint bleeds and patients' well-being in terms of improved quality of life (QoL), it is unclear whether or not prophylaxis influences the outcome and perception of well- of children with hemophilia.

Author-supplied keywords

  • Episodic treatment
  • Haemo-QoL
  • Hemarthrosis
  • Hemophilia A
  • Prophylaxis
  • Quality of life

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  • Alessandro Gringeri

  • B. Lundin

  • S. Von Mackensen

  • L. Mantovani

  • P. M. Mannucci

  • A. Billio

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