Randomized controlled trial to compare two bone substitutes in the treatment of bony dehiscences

  • Van Assche N
  • Michels S
  • Naert I
 et al. 
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Abstract

AIM: This in vivo split-mouth randomized controlled trial compared a synthetic bone substitute with a bovine bone mineral to cover bone dehiscences after implant insertion.

MATERIALS AND METHODS: Fourteen patients received four to six implants to support an overdenture. Two comparable dehiscences within the same patient were first covered with a layer of autogenous bone, followed by a layer of either Bio-Oss® (group 1; Geistlich Pharma AG, Wolhusen, Switzerland) or Straumann BoneCeramic® (group 2; Institut Straumann AG, Basel, Switzerland) and sealed by a resorbable membrane. The change in vertical dimension of the defect was measured at implant placement and at abutment connection (6.5 months). Clinical and radiological parameters were evaluated up to 1 year of loading.

RESULTS: The vertical size of the defect at surgery was 6.4 ± 1.6 mm for group 1 and 6.4 ± 2.2 mm for group 2 sites, measured from the implant shoulder. After 6.5 months, the depth of the defect was reduced to 1.5 ± 1.2 mm and 1.9 ± 1.2 mm for group 1 and group 2 sites, respectively (p > 0.05). No implants failed during follow-up. Mean marginal bone loss over the SLActive surface was 0.94 mm (group 1), 0.81 mm (group 2), and 0.93 mm (group 3, no dehiscence) after 1 year of loading.

CONCLUSION: Both bone substitutes behaved equally effectively.

Author-supplied keywords

  • Bone augmentation
  • Guided bone regeneration
  • Maxilla
  • SLActive
  • Two stage

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Authors

  • Nele Van Assche

  • Sofie Michels

  • Ignace Naert

  • Marc Quirynen

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