Rapid fabrication of electrochemical enzyme sensor chip using polydimethylsiloxane microfluidic channel

  • Yamaguchi A
  • Jin P
  • Tsuchiyama H
 et al. 
  • 3


    Mendeley users who have this article in their library.
  • N/A


    Citations of this article.


Applicability of polydimethylsiloxane (PDMS) for easy and rapid fabrication of enzyme sensor chips, based on electrochemical detection, is examined. The sensor chip consists of PDMS substrate with a microfluidic channel fabricated in it, and a glass substrate with enzyme-modified microelectrodes. The two substrates are clamped together between plastic plates. The sensor chip has shown no leakage around the microelectrodes under continuous solution flow (34 mul/min). Amperometric response of the sensor chips developed in this work suggest that various types of enzyme sensors can be designed by using PDMS microfluidic channels. (C) 2002 Elsevier Science B.V. All rights reserved.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • A Yamaguchi

  • P Jin

  • H Tsuchiyama

  • T Masuda

  • K Sun

  • S Matsuo

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free