Reactive supramolecular assemblies of mucopolysaccharide, polypyrrole and protein as controllable biocomposites for a new generation of 'intelligent biomaterials'

Abstract

A method for the simple synthesis of supramolecular composites of polypyrrole, complex mucopolysaccharides and protein is described. These materials have interesting hydrogel-like properties such as high water content and biocompatibility. In addition they are capable of trapping protein in their structure during synthesis and releasing this protein in response to electrical stimuli. The materials are also electroconductive and electroactive. The improved mechanical properties of polypyrrole films over hydrogels and the facile control of their properties by the application of small electrical potentials make them interesting candidates for the design and synthesis of a new generation of 'smarter' biomaterials. © 1995.