Reduced GABAergic Action in the Autistic Brain

  • Robertson C
  • Ratai E
  • Kanwisher N
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Abstract

An imbalance in inhibitory/excitatory neurotransmission is proposed to affect the autistic brain, but empirical evidence in humans is lacking. Robertson et al. report a link between a robust autistic perceptual symptom and reduced action of the inhibitory neurotransmitter, γ-aminobutyric acid (GABA), in the brains of autistic individuals.

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Authors

  • Caroline E. Robertson

  • Eva Maria Ratai

  • Nancy Kanwisher

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