Reduced survival with increasing plasma osmolality in elderly continuing-care patients

  • O'neill P
  • Faragher E
  • Davies I
 et al. 
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The results reported here are from a 2-year follow-up study of 58 elderly patients in a continuing-care unit. Most of these patients were in a hyperosmolar state at the time of entry (mean plasma osmolality 304+/-8 mOsmol/kg). The survival of those patients with the highest osmolality (>308 mOsmol/kg) was significantly reduced (p=0.025), with an increased mortality at 2 years (15/20 patients, p=0.053). There was no correlation between age and plasma osmolality (r=0.02) and the effect of osmolality on survival was independent of age. Hyperosmolality was either a marker for, or a cause of, increased mortality in this group of frail elderly patients

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  • P. A. O'neill

  • E. B. Faragher

  • I. Davies

  • R. Wears

  • K. A. Mclean

  • D. S. Fairweather

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