There are currently at least forty-six unique protein kinase crystal structures, twenty-four of which are available in an active state. Here we examine these structures using a structural bioinformatics approach to understand how the confromation of the activation segment controls kinase activity.
CITATION STYLE
Nolen, B., Taylor, S., & Ghosh, G. (2004, September 10). Regulation of protein kinases: Controlling activity through activation segment conformation. Molecular Cell. https://doi.org/10.1016/j.molcel.2004.08.024
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