The relationship of blood lead levels to blood pressure in the U.S. population

  • Harlan W
  • 1


    Mendeley users who have this article in their library.
  • N/A


    Citations of this article.


Numerous observations have indicated a relationship between moderate or heavy lead exposure and high blood pressure. To determine whether low-level lead exposure is related to blood pressure in the U.S. population, we analyzed data from the National Health and Nutrition Examination Survey II for persons 12 to 74 years of age. Significant correlations were found between blood lead and blood pressure for each race-gender group, and blood lead levels were significantly higher in groups with high diastolic blood pressure (greater than 90 mm Hg). Multiple stepwise regression models were developed to predict blood pressure. After adjusting for age, race, and body mass index, blood lead levels were significantly related to systolic and diastolic pressures in males but not in females. These findings and those from other studies confirm the relationship of blood lead and blood pressure at relatively low levels commonly observed in the general population. The strength and importance of this relationship require further study through epidemiologic and metabolic investigations.

Author-supplied keywords

  • Adolescent
  • Adult
  • Aged
  • Blood Pressure/*drug effects
  • Child
  • Environmental Exposure
  • Female
  • Health Surveys
  • Humans
  • Lead/*blood/pharmacology
  • Male
  • Middle Aged
  • United States

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • William R Harlan

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free