The role of neuroimaging in evaluating patients affected by Creutzfeldt-Jakob disease: a systematic review of the literature.

  • Caobelli F
  • Cobelli M
  • Pizzocaro C
 et al. 
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Abstract

Diagnosis of Creutzfeldt-Jakob disease during life can be challenging since the huge variability of the symptoms which can be observed, especially in its early stages, may simulate other common forms of dementia. In latest years, noninvasive techniques such as magnetic resonance, positron emission tomography, and single-photon emission tomography have been evaluated to help clinical neurologists to provide a definite diagnosis. We here provide a systematic review of the current knowledge of neuroimaging in CJD in order to establish the actual state of the art.

Author-supplied keywords

  • Brain
  • Brain: pathology
  • Brain: radionuclide imaging
  • Creutzfeldt-Jakob Syndrome
  • Creutzfeldt-Jakob Syndrome: diagnosis
  • Evidence-Based Medicine
  • Humans
  • Magnetic Resonance Imaging
  • Magnetic Resonance Imaging: methods
  • Neuroimaging
  • Neuroimaging: methods
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Tomography, Emission-Computed
  • Tomography, Emission-Computed: methods

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Authors

  • Federico Caobelli

  • Milena Cobelli

  • Claudio Pizzocaro

  • Marco Pavia

  • Silvia Magnaldi

  • Ugo Paolo Guerra

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