The role of radiotherapy for metastatic epidural spinal cord compression

  • D. R
  • J.L. A
  • 2

    Readers

    Mendeley users who have this article in their library.
  • N/A

    Citations

    Citations of this article.

Abstract

Radiotherapy alone is the most common treatment for metastatic epidural spinal cord compression (MESCC). Decompressive surgery followed by radiotherapy is generally indicated only in 10-15% of MESCC cases. Chemotherapy has an unclear role and may be considered for selected patients with hematological or germ-cell malignancies. If radiotherapy alone is given, it is important to select the appropriate regimen. Similar functional outcomes can be achieved with short-course radiotherapy regimens and longer-course radiotherapy regimens. Longer-course radiotherapy is associated with better local control of MESCC than short-course radiotherapy. Patients with a more favorable survival prognosis (expected survival of 6 months) should receive longer-course radiotherapy, as they may live long enough to develop a recurrence of MESCC. Patients with an expected survival of

Author-supplied keywords

  • *cancer radiotherapy
  • *metastatic epidural spinal cord compression/di [D
  • *metastatic epidural spinal cord compression/dt [D
  • *metastatic epidural spinal cord compression/et [E
  • *metastatic epidural spinal cord compression/rt [R
  • *metastatic epidural spinal cord compression/su [S
  • *spinal cord compression/di [Diagnosis]
  • *spinal cord compression/dt [Drug Therapy]
  • *spinal cord compression/et [Etiology]
  • *spinal cord compression/rt [Radiotherapy]
  • *spinal cord compression/su [Surgery]
  • *spine metastasis/di [Diagnosis]
  • *spine metastasis/dt [Drug Therapy]
  • *spine metastasis/et [Etiology]
  • *spine metastasis/rt [Radiotherapy]
  • *spine metastasis/su [Surgery]
  • CyberKnife
  • bone metastasis/rt [Radiotherapy]
  • cancer chemotherapy
  • cancer recurrence
  • clinical trial
  • computer assisted tomography
  • decompression surgery
  • delirium/si [Side Effect]
  • dexamethasone/ae [Adverse Drug Reaction]
  • dexamethasone/ct [Clinical Trial]
  • dexamethasone/dt [Drug Therapy]
  • dexamethasone/iv [Intravenous Drug Administration]
  • dexamethasone/po [Oral Drug Administration]
  • differential diagnosis
  • fentanyl citrate/dt [Drug Therapy]
  • functional status
  • gastrointestinal hemorrhage/si [Side Effect]
  • human
  • hydromorphone/dt [Drug Therapy]
  • hyperglycemia/si [Side Effect]
  • insomnia/si [Side Effect]
  • intensity modulated radiation therapy
  • intervertebral disk degeneration
  • loading drug dose
  • methadone/dt [Drug Therapy]
  • morphine/dt [Drug Therapy]
  • motor dysfunction
  • myelography
  • nonhuman
  • nuclear magnetic resonance imaging
  • overall survival
  • oxycodone/dt [Drug Therapy]
  • pain/dt [Drug Therapy]
  • pathologic fracture
  • pathophysiology
  • priority journal
  • prognosis
  • psychosis/si [Side Effect]
  • psychosocial care
  • radiation dose fractionation
  • radicular pain
  • retreatment
  • review
  • spine radiography
  • stereotactic body radiation therapy
  • survival rate
  • treatment duration
  • ulcer/si [Side Effect]
  • vertebra dislocation
  • vertebra fracture
  • visceral metastasis

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Authors

  • Rades D.

  • Abrahm J.L.

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free