The role of radiotherapy for metastatic epidural spinal cord compression

  • D. R
  • J.L. A
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Radiotherapy alone is the most common treatment for metastatic epidural spinal cord compression (MESCC). Decompressive surgery followed by radiotherapy is generally indicated only in 10-15% of MESCC cases. Chemotherapy has an unclear role and may be considered for selected patients with hematological or germ-cell malignancies. If radiotherapy alone is given, it is important to select the appropriate regimen. Similar functional outcomes can be achieved with short-course radiotherapy regimens and longer-course radiotherapy regimens. Longer-course radiotherapy is associated with better local control of MESCC than short-course radiotherapy. Patients with a more favorable survival prognosis (expected survival of 6 months) should receive longer-course radiotherapy, as they may live long enough to develop a recurrence of MESCC. Patients with an expected survival of

Author-supplied keywords

  • *cancer radiotherapy
  • *metastatic epidural spinal cord compression/di [D
  • *metastatic epidural spinal cord compression/dt [D
  • *metastatic epidural spinal cord compression/et [E
  • *metastatic epidural spinal cord compression/rt [R
  • *metastatic epidural spinal cord compression/su [S
  • *spinal cord compression/di [Diagnosis]
  • *spinal cord compression/dt [Drug Therapy]
  • *spinal cord compression/et [Etiology]
  • *spinal cord compression/rt [Radiotherapy]
  • *spinal cord compression/su [Surgery]
  • *spine metastasis/di [Diagnosis]
  • *spine metastasis/dt [Drug Therapy]
  • *spine metastasis/et [Etiology]
  • *spine metastasis/rt [Radiotherapy]
  • *spine metastasis/su [Surgery]
  • CyberKnife
  • bone metastasis/rt [Radiotherapy]
  • cancer chemotherapy
  • cancer recurrence
  • clinical trial
  • computer assisted tomography
  • decompression surgery
  • delirium/si [Side Effect]
  • dexamethasone/ae [Adverse Drug Reaction]
  • dexamethasone/ct [Clinical Trial]
  • dexamethasone/dt [Drug Therapy]
  • dexamethasone/iv [Intravenous Drug Administration]
  • dexamethasone/po [Oral Drug Administration]
  • differential diagnosis
  • fentanyl citrate/dt [Drug Therapy]
  • functional status
  • gastrointestinal hemorrhage/si [Side Effect]
  • human
  • hydromorphone/dt [Drug Therapy]
  • hyperglycemia/si [Side Effect]
  • insomnia/si [Side Effect]
  • intensity modulated radiation therapy
  • intervertebral disk degeneration
  • loading drug dose
  • methadone/dt [Drug Therapy]
  • morphine/dt [Drug Therapy]
  • motor dysfunction
  • myelography
  • nonhuman
  • nuclear magnetic resonance imaging
  • overall survival
  • oxycodone/dt [Drug Therapy]
  • pain/dt [Drug Therapy]
  • pathologic fracture
  • pathophysiology
  • priority journal
  • prognosis
  • psychosis/si [Side Effect]
  • psychosocial care
  • radiation dose fractionation
  • radicular pain
  • retreatment
  • review
  • spine radiography
  • stereotactic body radiation therapy
  • survival rate
  • treatment duration
  • ulcer/si [Side Effect]
  • vertebra dislocation
  • vertebra fracture
  • visceral metastasis

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  • Rades D.

  • Abrahm J.L.

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