The role of specific Toxoplasma gondii molecules in manipulation of innate immunity

  • Pollard A
  • Knoll L
  • Mordue D
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Abstract

Infection with the parasite Toxoplasma gondii stimulates an innate immune response in the host. T. gondii also induces alterations in infected monocytes and dendritic cells that probably contribute to its ability to disseminate and ultimately to establish persistent infection. Recent progress has linked specific parasite molecules to immune stimulation or the ability of the parasite to subvert intracellular signaling pathways in infected cells to evade immunity. © 2009 Elsevier Ltd. All rights reserved.

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Authors

  • Angela M. Pollard

  • Laura J. Knoll

  • Dana G. Mordue

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