Safety of influenza vaccination in allergic children

  • Bierman C
  • Shapiro G
  • Pierson W
 et al. 
  • 7


    Mendeley users who have this article in their library.
  • 68


    Citations of this article.


One hundred forty-two allergic children aged three to 18 years were studied for evaluation of the usefulness of skin testing with influenza vaccine as a means of identifying those children who could be immunized safely despite their allergies to chickens, eggs, or feathers. One hundred twenty-eight children were fully immunized with bivalent influenza A/New Jersey/76-A/Victoria/75 vaccine. Twelve children had positive skin tests and were not immunized, and two developed positive skin tests after their first injection. One child had urticaria 8 hr later, one had a nonspecific reaction, and one had a self-limited erythema multiforme reaction eight days after the second injection. All others tolerated the procedure well. History of sensitivity to eggs was not as reliable an indication of vaccine sensitivity as skin testing with vaccine. A negative result of an intradermal skin test with a 1:100 dilution of the vaccine in saline appeared to be a reliable indicator of allergic subjects who could be immunized against influenza without fear of life-threatening acute allergic reactions.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • C. Warren Bierman

  • Gail G. Shapiro

  • William E. Pierson

  • John W. Taylor

  • Hjordis M. Foy

  • John P. Fox

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free