Sample size requirements for stratified cluster randomization designs

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Sample size requirements are provided for designs of studies in which clusters are randomized within each of several strata, where cluster size itself may be a stratifying factor. The approach generalizes a formula derived by Woolson et al., which provides sample size requirements for the Cochran-Mantel-Haenszel statistic. Issues of data analysis are also discussed.

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  • Allan Donner

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