Sclerosing perineurioma: Tumor of the hand with a short T2

  • Miyake M
  • Tateishi U
  • Maeda T
 et al. 
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We present two cases of sclerosing perineurioma, a rare soft tissue tumor, in the palm and the ring finger respectively, presenting as a small, painless and subcutaneous mass. This tumor has a predilection for the digits and palms of young, predominantly male adults. In the present cases the tumors showed very low signal intensity on T2-weighted magnetic resonance (MR) images. Histologically they contained abundant collagen and hyalinized stroma, which would account for areas of low signal intensity on T2-weighted MR images. Immunohistochemically, the tumor cells were positive for vimentin, epithelial membrane antigen and human erythrocyte glucose transporter 1 and negative for S-100 protein. To the best of our knowledge, the appearance of sclerosing perineurioma on MR imaging has not been previously reported in the English-language literature. Sclerosing perineurioma should be considered in the differential diagnosis of hand tumors when the tumor shows low signal intensity on T2-weighted MR images.

Author-supplied keywords

  • Hand
  • MRI
  • Sclerosing perineurioma
  • Short T2

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  • Mototaka Miyake

  • Ukihide Tateishi

  • Tetsuo Maeda

  • Yasuaki Arai

  • Kunihiko Seki

  • Tadashi Hasegawa

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