Selection in the evolution of gene duplications

  • Kondrashov F
  • Rogozin I
  • Wolf Y
 et al. 
  • 11

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Abstract

Gene duplications have a major role in the evolution of new biological functions. Theoretical studies often assume that a duplication per se is selectively neutral and that, following a duplication, one of the gene copies is freed from purifying (stabilizing) selection, which creates the potential for evolution of a new function.

Author-supplied keywords

  • Animals
  • Evolution
  • Gene Duplication
  • Genetic
  • Humans
  • Mice
  • Molecular
  • Rats
  • Selection

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Authors

  • Fyodor a Kondrashov

  • Igor B Rogozin

  • Yuri I Wolf

  • Eugene V Koonin

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