Selective expansion of influenza A virus-specific T cells in symptomatic human carotid artery atherosclerotic plaques

  • Keller T
  • Van Der Meer J
  • Teeling P
 et al. 
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Evidence is accumulating that infection with influenza A virus contributes to atherothrombotic disease. Vaccination against influenza decreases the risk of atherosclerotic syndromes, indicating that inflammatory mechanisms may be involved. We tested the hypothesis that influenza A virus-specific T cells contribute to atherosclerotic plaque inflammation, which mediates the onset of plaque rupture.

Author-supplied keywords

  • Atherosclerosis
  • Carotid artery
  • Infectious disease
  • Influenza
  • T lymphocytes

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  • Tymen T. Keller

  • Jelger J. Van Der Meer

  • Peter Teeling

  • Koen Van Der Sluijs

  • Mirza M. Idu

  • Guus F. Rimmelzwaan

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