Self replicating systems

  • Patzke V
  • von Kiedrowski G
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Abstract

Chemical self-replicating systems have been the subject of various investigations over the last 20 years. This mini review outlines the design of minimal model systems, mainly based on oligonucleotides and on peptides and artificial compounds, which implement template-directed reactions. In order to examine the reaction mechanism and to attain an exponential replication the development of self-replicating systems is pointed out.

Author-supplied keywords

  • ANALOGS
  • CHEMICAL LIGATION
  • CHEMISTRY
  • DNA DUPLEXES
  • EVOLUTION
  • EXPONENTIAL-GROWTH
  • HEXADEOXYNUCLEOTIDE
  • INFORMATION
  • PEPTIDE
  • RNA
  • autocatalysis
  • cross-catalysis
  • oligonucleotides
  • reaction mechanism
  • self-replication
  • template-directed reactions

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Authors

  • Volker Patzke

  • Guenter von Kiedrowski

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