Self-assembly of cyclodextrins: Formation of cyclodextrin polymer based nanoparticles

  • Fülöp Z
  • Kurkov S
  • Nielsen T
 et al. 
  • 28

    Readers

    Mendeley users who have this article in their library.
  • 14

    Citations

    Citations of this article.

Abstract

The design of functional cyclodextrin (CD) nanoparticles is a developing area in the field of nanomedicine. CDs can not only help in the formation of drug carriers but also increase the local concentration of drugs at the site of action. CD monomers form aggregates by self-assembly, a tendency that increases upon formation of inclusion complexes with lipophilic drugs. However, the stability of such aggregates is not sufficient for parenteral administration. In this review CD polymers and CD containing nanoparticles are categorized, with focus on self-assembled CD nanoparticles. It is described how the nanoparticles can be stabilized and tuned to have specific properties.

Author-supplied keywords

  • Aggregation
  • Cyclodextrin polymers
  • Cyclodextrins
  • Nanoparticles
  • Self-assembly
  • Stabilization

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free