Sequence of the PAS8 gene, the product of which is essential for biogenesis of peroxisomes in Saccharomyces cerevisiae

  • Voorn-Brouwer T
  • van der Leij I
  • Hemrika W
 et al. 
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Abstract

In a genetic screen for mutants disturbed in peroxisomal functions we found that the laboratory 'wild type' strain YP102 behaved like a typical peroxisome assembly mutant. Here, we report the sequence of the complementing gene (PAS8), coding for a protein of 1030 amino acids that appears to be a novel member of the AAA-protein family which also includes NSFp and PAS1p. © 1993.

Author-supplied keywords

  • (Yeast)
  • AAA-protein family
  • Gene sequence
  • Organelle assembly
  • Peroxisome, pas8 gene

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Authors

  • Tineke Voorn-Brouwer

  • Inge van der Leij

  • Wieger Hemrika

  • Ben Distel

  • Henk F. Tabak

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