Severe traumatic brain injury

  • Finfer S
  • Cohen J
  • S.R. F
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Abstract

In western countries, injuries remain the leading cause of death in young adults (Jennett B. Epidemiology of head injury. J Neurol Neurosurg Psychiatry 1996; 60: 362-369). Worldwide, injuries are estimated to account for 15% of the burden of death and disability, and are projected to account for 20% in 2020 (Ad Hoc Committee on Health Research Relating to Future Intervention Options. Investing in Health Research and Development (Document TDR/Gen/96.1). Geneva: World Health Organisation, 1996). In developing countries road traffic injuries in particular are increasing in incidence and injuries are projected to be the third leading cause of death and disability worldwide by 2020 (Ad Hoc Committee on Health Research Relating to Future Intervention Options. Investing in Health Research and Development (Document TDR/Gen/96.1). Geneva: World Health Organisation, 1996). Head injury accounts for up to half of all deaths from trauma (Kraus J. Epidemiology of head injury. In: Cooper PR, Ed. Head Injury, 3rd ed. Baltimore, MD: William Wilkins, 1993), and in addition to causing death often causes severe and long-lasting functional impairment in survivors. © 2001 Elsevier Science Ireland Ltd.

Author-supplied keywords

  • *Brain Injuries/di [Diagnosis]
  • *Brain Injuries/th [Therapy]
  • *Cause of Death
  • *Critical Care/mt [Methods]
  • *Emergency Medical Services/mt [Methods]
  • *adult
  • *brain injury/di [Diagnosis]
  • *brain injury/dt [Drug Therapy]
  • *brain injury/ep [Epidemiology]
  • *brain injury/et [Etiology]
  • *brain injury/su [Surgery]
  • *brain injury/th [Therapy]
  • *cytokine/ec [Endogenous Compound]
  • *injury
  • *intensive care
  • *traumatic brain injury
  • 21 aminosteroid
  • Accidental Falls
  • Accidents
  • Adolescent
  • Adult
  • Australia/ep [Epidemiology]
  • Brain Injuries/et [Etiology]
  • Brain Injuries/mo [Mortality]
  • Combined Modality Therapy
  • Doppler echography
  • Female
  • Glasgow Coma Scale
  • Glasgow coma scale
  • Humans
  • Injury Severity Score
  • Male
  • Prognosis
  • Risk Factors
  • Survival Analysis
  • Traffic
  • United States
  • apolipoprotein E/ec [Endogenous Compound]
  • article
  • barbituric acid derivative
  • cause of death
  • coma
  • death
  • decompression surgery
  • developing country
  • disability
  • disease severity
  • epidemiology
  • functional disease
  • functional disease/et [Etiology]
  • furosemide/dt [Drug Therapy]
  • genetic polymorphism
  • head injury
  • health
  • human
  • interleukin 1/ec [Endogenous Compound]
  • interleukin 6/ec [Endogenous Compound]
  • intracranial pressure
  • mannitol/dt [Drug Therapy]
  • medical research
  • n methyl dextro aspartic acid receptor/ec [Endogen
  • nimodipine/dt [Drug Therapy]
  • nitric oxide/ec [Endogenous Compound]
  • oximetry
  • pathophysiology
  • patient
  • patient transport
  • priority journal
  • psychiatry
  • subarachnoid hemorrhage/et [Etiology]
  • traffic
  • traffic accident
  • treatment outcome
  • tumor necrosis factor/ec [Endogenous Compound]
  • valerian

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Authors

  • S R Finfer

  • J Cohen

  • Finfer S.R.

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