Sex Determination in Caenorhabditis elegans

  • Kuwabara P
  • Kimble J
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Abstract

In Caenorhabditis elegans, the decision to develop as a hermaphrodite or male is controlled by a cascade of regulatory genes. These genes and other tissue-specific regulatory genes also control sexual fate in the hermaphrodite germline, which makes sperm first and then oocytes. In this review, we summarize the genetic and molecular characterization of these genes and speculate how they mutually interact to specify sexual fate.

Author-supplied keywords

  • as an experimental organism
  • c
  • caenorhabditis elegans
  • caenorhabditis elegans is a
  • culture
  • free-living soil
  • hermaphrodite
  • laboratory
  • nematode
  • nematode easily maintained in
  • sex determination

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Authors

  • Patricia E Kuwabara

  • J Kimble

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