Simple simulator to teach enzyme kinetics dynamics. Application in a Problem-Solving exercise

  • Torres N
  • Santos G
  • 3


    Mendeley users who have this article in their library.
  • 0


    Citations of this article.


© 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Enzyme kinetics is an essential part of biochemistry programs, which have been gaining importance in recent years for their applications in biotechnology and biomedicine. The teaching and learning of these issues has been traditionally hampered by difficulties that stem mainly from the dynamic and mathematical nature of the topic and the introduction of some abstract concepts. In this paper, we propose a simple, home-made application developed in Excel or, alternatively, in Libre Office (SIMENKIN), which allows students to view and interact with the dynamics of enzymatic reactions. The contribution of this specific application stems from the simulation of substrate loss and the associated initial rate of the enzyme catalysed reaction over time, which is not always incorporated into these packages. We illustrate its use applying it in a practical problem-solving approach module, designed to facilitate the learning of the fundamental concepts of enzyme kinetics.

Author-supplied keywords

  • Biosciences
  • Enzyme kinetics
  • Michaelis-Menten model
  • Problem-solving approach

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text


  • Néstor Torres

  • Guido Santos

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free