A small catalytic oligoribonucleotide

  • Uhlenbeck O
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A 19-nucleotide RNA fragment can cause rapid, highly specific cleavage of a 24-nucleotide RNA fragment under physiological conditions. Because each 19-mer can participate in many cleavage reactions, this molecule has all the properties associated with an RNA enzyme.

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  • Olke C. Uhlenbeck

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