Ependymomas are tumours that arise throughout the central nervous system. Little is known regarding the aberrant cellular and molecular processes that generate these tumours. This lack of knowledge has hampered efforts to reduce the significant mortality and morbidity that are associated with ependymoma. Here, we review recent data that suggest that radial glia are cells of origin of ependymoma, and discuss the processes that might transform these neural progenitors into ependymoma cancer stem cells. © 2007 Cancer Research UK.
CITATION STYLE
Poppleton, H., & Gilbertson, R. J. (2007, January 15). Stem cells of ependymoma. British Journal of Cancer. https://doi.org/10.1038/sj.bjc.6603519
Mendeley helps you to discover research relevant for your work.