Skip to content
Journal article

Studies on Liver-toxicity in Rhigoma of Dioscorea bulbifera

Tan X, Ruan J, Chen H, Wang J ...see all

China Journal of Chinese Materia Medica, vol. 28, issue 7 (2003) pp. 661-663

  • 6


    Mendeley users who have this article in their library.
  • 7


    Citations of this article.
  • N/A


    ScienceDirect users who have downloaded this article.
Sign in to save reference


To explore the liver-toxic fraction in Rhigoma of Dioscorea bulbifera.The rats were randomized into four groups: control group (20% PVP-water), T001(10% total methanol extraction), F002(5% chloroform fraction) and F003(5% methanol fraction). Direct bilirubin (DBil) and Glutamic-pyruvic transaminase (GPT) were examined, and liver index was measured. The histological and morphological observations were performed with optical and electrical microscope.T001 and F002 showed significant liver toxicity.The chloroform fraction was the liver-toxic fraction of D. bulbifera.

Find this document


  • Xingqi Tan

  • Jinlan Ruan

  • Haisheng Chen

  • Juying Wang

Cite this document

Choose a citation style from the tabs below