Journal article

Suplementação e uso terapêutico de vitamina D nos pacientes com esclerose múltipla: Consenso do Departamento Científico de Neuroimunologia da Academia Brasileira de Neurologia

Brum D, Comini-Frota E, Vasconcelos C, Dias-Tosta E ...see all

Arquivos de Neuro-Psiquiatria, vol. 72, issue 2 (2014) pp. 152-156 Published by Arquivos de Neuro-Psiquiatria

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Abstract

Multiple sclerosis (MS) is an inflammatory, autoimmune, demyelinating,
and degenerative central nervous system disease. Even though the
etiology of MS has not yet been fully elucidated, there is evidence that
genetic and environmental factors interact to cause the disease. Among
the main environmental factors studied, those more likely associated
with MS include certain viruses, smoking, and hypovitaminosis D. This
review aimed to determine whether there is evidence to recommend the use
of vitamin D as monotherapy or as adjunct therapy in patients with MS.
We searched PUBMED, EM BASE, COCHRANNE, and LILACS databases for studies
published until September 9th, 2013, using the keywords ``multiple
sclerosis{''} ``vitamin D{''}, and ``clinical trial{''}. There is no
scientific evidence up to the production of this consensus for the use
of vitamin D as monotherapy for MS in clinical practice.

Author-supplied keywords

  • Experimental autoimmune encephalitis
  • Multiple sclerosis
  • Vitamin D

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