Surgical outcomes of primary hip and knee replacements in patients with Parkinson's disease: a nationwide registry-based case-controlled study.

  • Jämsen E
  • Puolakka T
  • Peltola M
 et al. 
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We evaluated the duration of hospitalisation, occurrence of infections, hip dislocations, revisions, and mortality following primary hip and knee replacement in 857 patients with Parkinson's disease and compared them with 2571 matched control patients. The data were collected from comprehensive nationwide Finnish health registers. The mean follow-up was six years (1 to 13). The patients with Parkinson's disease had a longer mean length of stay (21 days [1 to 365] vs 13 [1 to 365] days) and an increased risk for hip dislocation during the first post-operative year (hazard ratio (HR) 2.33, 95% confidence intervals (CI) 1.02 to 5.32). There was no difference in infection and revision rates, and one-year mortality. In longer follow-up, patients with Parkinson's disease had higher mortality (HR 1.94, 95% CI 1.68 to 2.25) and only 274 (34.7%) were surviving ten years after surgery. In patients with Parkinson's disease, cardiovascular and psychiatric comorbidity were associated with prolonged hospitalisation and cardiovascular diseases also with increased mortality. Cite this article: Bone Joint J 2014;96-B:486-91.

Author-supplied keywords

  • Aged
  • Aged, 80 and Over
  • Arthroplasty, Replacement, Hip -- Adverse Effects
  • Arthroplasty, Replacement, Hip -- Mortality
  • Arthroplasty, Replacement, Knee -- Adverse Effects
  • Arthroplasty, Replacement, Knee -- Mortality
  • Case Control Studies
  • Data Collection
  • Female
  • Finland
  • Hip Dislocation -- Etiology
  • Hospitalization -- Statistics and Numerical Data
  • Human
  • Joint Prosthesis -- Adverse Effects
  • Kaplan-Meier Estimator
  • Length of Stay -- Statistics and Numerical Data
  • Male
  • Middle Age
  • Osteoarthritis, Hip -- Complications
  • Osteoarthritis, Hip -- Mortality
  • Osteoarthritis, Hip -- Surgery
  • Osteoarthritis, Knee -- Complications
  • Osteoarthritis, Knee -- Mortality
  • Osteoarthritis, Knee -- Surgery
  • Parkinson Disease -- Complications
  • Parkinson Disease -- Mortality
  • Prosthesis-Related Infections -- Etiology
  • Prosthesis-Related Infections -- Mortality
  • Reoperation -- Statistics and Numerical Data
  • Risk Factors
  • Treatment Outcomes

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  • E Jämsen

  • T Puolakka

  • M Peltola

  • A Eskelinen

  • M U K Lehto

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