Survival after Initial Diagnosis of Alzheimer Disease

  • Larson E
  • Marie-Florence S
  • Wang L
 et al. 
  • 3


    Mendeley users who have this article in their library.
  • N/A


    Citations of this article.


Larson et al investigate the course of Alzheimer disease after initial diagnosis and examine associations hypothesized to correlate with survival among community-dwelling patients with Alzheimer disease. Results demonstrate that survival duration was shorter than predicted on the basis of US population data, especially for persons with onset at relatively younger ages in this sample of community-dwelling elderly persons who received a diagnosis of Alzheimer disease. Features significantly associated with reduced survival at diagnosis were increased severity of cognitive impairment, decreased functional level, history of falls, physical examination findings of frontal release signs, and abnormal gait.

Author-supplied keywords

  • Aged
  • Aged, 80 & over
  • Alzheimer Disease -- diagnosis
  • Alzheimer Disease -- mortality
  • Comorbidity
  • Female
  • Humans
  • Life Expectancy
  • Male
  • Medical Sciences
  • Middle Aged
  • Prognosis
  • Proportional Hazards Models
  • Research Support, U.S. Gov't, P.H.S.
  • Severity of Illness Index
  • Survival Rate
  • United States -- epidemiology

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Eric B Larson

  • Shadlen Marie-Florence

  • Li Wang

  • Wayne C McCormick

  • et al.

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free